VAL-083 - CAS# 23261-20-3 inone I Targeting BCR-ABL1 in Chronic Myeloid

Targeting BCR-ABL1 in Chronic Myeloid Leukemia by PROTAC-Mediated Targeted Protein Degradation

is a very potent 5-HT7 receptor antagonist

Varenicline (2

4)35(39)23(17-41(26

RA-9 selectively induces apoptosis in ovarian cancer cell lines

VAL-083 - CAS# 23261-20-3 inone I Targeting BCR-ABL1 in Chronic MyeloidVAL 083 is a bi functional alkylating agent, with potential antineoplastic activity. Upon administration, VAL 083 crosses the blood brain barrier (BBB) and appears to be selective for tumor cells. This agent alkylates and crosslinks DNA which ultimately leads to a reduction in cancer cell proliferation. In addition, VAL 083 does not show cross resistance to other conventional chemotherapeutic agents and has a long half life in the brain. Product