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Ringseis R
InChiKey: QRJTZIJWDLJKQO-UHFFFAOYSA-N
Decreased activity and expression of the cardiac sarcoplasmic reticulum calcium ATPase (SERCA2a)
105(30):10595-600
S3I-201 significantly reduces viable cell numbers and inhibits growth of transformed mouse fibroblasts NIH 3T3/v-Src and breast carcinoma cell lines (MDA-MB-231
R-(+)-ETOMOXIR - CAS# 124083-20-1 093 Ringseis RR (+) ETOMOXIR, CAS No. 124083 20 1, is an irreversible inhibitor of carnitine palmitoyltransferase 1 (CPT 1) on the outer face of the inner mitochondrial membrane. This prevents the formation of acyl carnitines, a step that is necessary for the transport of fatty acyl chains from the cytosol into the intermembrane space of the mitochondria. This step is essential to the production of ATP from fatty acid oxidation. Etomoxir has also been identified as