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The text is very specific it prevents activations and does not negate activated effects

Lands obviously cant be cast, but many cards that reward you for casting spells from exile offer the same benefit when you play a land from exile

You can only use each effect of "Pride HERO Rainbowpoly Xenogender" once per turn SPELL/TRAPS: When this card is activated: You can excavate the top 5 cards of your Deck, add 1 excavated "Pride HERO" card to your hand, also send any other "HERO" cards to the GY, and shuffle the remaining cards into the Deck

Golduck 41/236 is a Uncommon card and belongs to Uncommon cards of Cosmic Eclipse series

(If a permanent with a stun counter would become untapped, remove one from it instead.) You may target a creature that is already tapped with Tranquilize