The two big factors that make Liliana substantially better than Mind Rot and company are that she stays in play and that she can Cruel Edict for -2 loyalty
Board wipes usually put every player in the game at a disadvantage, which might seem bad
However, this deck is also a tokens deck, and its MTG commander, Hazel of the Rootbloom, can tap your tokens for mana while also copying tokens - making two copies if that token was a squirrel
But if you can activate abilities, then as soon as you have priority (and enough mana) and decide to sac the Clue, then poof , it's gone, nothing I can do to stop it
This is true whether it enters the battlefield after being cast or in any other way, such as being put onto the battlefield with a card like [autocard]Rise from the Grave[/autocard]