Not Trinisphere, which is one of the best artifacts you can keep in your sideboard to tutor up with Karn, the Great Creator in various flavors and formats of Tron decks, which harness the mana generation power of Urza's Mine, Urza's Power Plant, Urza's Tower, and baby of the bunch Urza's Workshop when it's legal
Then up to one other target attacking creature gets +X/+0 until end of turn, where X is Amy Roses power
Chaos Warp Playing a Chaos Warp on an opponents best permanent to make them shuffle it into their library could very well backfire if they flip something worse off the top, but red has to deal with enchantments somehow
You might summon a fiery dragon to incinerate your opponents forces or cast a spell that freezes them in place with your pre-approved MTG custom tokens
Also, they have to draw the line somewhere