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When mutated onto a non-human creature, it produces solid removal potential as well as lifegain

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Or an Infinity Gauntlet card with a specific alternate win condition

Creature - Cleric Phyrexian Color tag templates(None) Vampire Nighthawk Flying Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.) Lifelink (Damage dealt by this creature also causes you to gain that much life.) Creature - Vampire Shaman Color tag templates(None) Wall of Essence Defender (This creature can't attack.) Whenever this creature is dealt combat damage, you gain that much life

Here we see a situation akin to when Luis held back his Elvish Mystics for fear of Patrick's Izzet Staticaster, but with different zones