Granting them vigilance and unblockable is pretty good in these decks, so Pym Particles has a home
I think that the Frenzy version is better against black-based midrange decks and ground-based creature decks, so I would say it is better against Rakdos Midrange, Mono White Humans and Rakdos Sacrifice
From a card design standpoint, this is captured with the creation of the Daybound/Nightbound mechanic on werewolves
As noted above, prices are expected to be a bit volatile for the first couple weeks following launch
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