If you want to play a longer more mid-to-lategame style deck in Mono Red that interacts more with the table, well, it gets more challenging because it makes Mono Red's inherent weaknesses more glaring: subpar card draw and ramp, subpar answers to creatures, minimal options for enchantment removal, commander protection, and recursion, things that get more pronounced as the game progresses
This makes Professional Face-Breaker an exceptional card advantage engine, effectively allowing you to draw a card for 1 mana
If you enchant a creature with Indestructibility after Humility has entered the battlefield, this creature has Indestructible because Indestructibilitys timestamp is newer than that of Humility
This isn't as useful in Commander as it has been in Modern and Legacy, but it's worth remembering that in an emergency one red mana can get players out of plenty of situations
The rarest and most expensive cards in Magic are the ones that sit on the reserved list, but just because those cards are now a commodity doesnt mean players dont want to play with them