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The proliferation of Ba/F3 cells transformed with NSCLC related KIF5B-RET fusion is effectively suppressed by RET-IN-4 (compound 9) (IC50 of 19 nM)
48% and 36%
Chemical Name: 2-hydroxy-4-[(Z)-{1-hydroxy-4-[(5Z)-5-[(2E)-2-methyl-3-phenylprop-2-en-1-ylidene]-4-oxo-2-sulfanylidene-1
1200 and 210 nM
It can be obtained directly from fish oil and maternal milk
Nosiheptide lozine The proliferation of Ba/F3 cellsNosiheptide (Multhiomycin), a thiopeptide antibiotic produced by Streptomyces actuosus, inhibits bacterial protein synthesis and bears a unique indole side ring system and regiospecific hydroxyl groups on the characteristic macrocyclic core. Nosiheptide has been widely used as a feed additive for animal growth. Product information CAS Number: 56377 79 8 Molecular Weight: 1222. 36 Formula: C51H43N13O12S6 Chemical Name: 2 ({2 [(21E) 21 ethylidene 9,30