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D609 - CAS# 83373-60-8 tin-3'-sulfonate Med Lett Drugs Ther

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Med Lett Drugs Ther

InChiKey: ZNOVTXRBGFNYRX-STQMWFEESA-N

COC1=CC=CC=C1OC1C(=NC(=NC=1NS(=O)(=O)C1=CC=C(C=C1)C(C)(C)C)C1=NC=CC=N1)OCCO

In vivo administration of AG-490 causes murine myeloma tumor cell apoptosis but does not inhibit IL-12-mediated macrophage activation and IFN-γ production by lymphocytes

BML-284 (10 µM

D609 - CAS# 83373-60-8 tin-3'-sulfonate Med Lett Drugs TherD 609, also known as D 609 free, is a phospholipase C inhibitor potentially for the treatment of pancreatic cancer. D 609, an inhibitor of PC PLC and sphingomyelin synthase, strongly inhibited myogenic tone and had no effect on depolarization induced contraction. D 609 appeared to act by lowering cytoplasmic Ca(2+) concentration to levels below those that activate contraction. Product information CAS Number: 83373 60 8 Molecular Weight: 266. 46

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