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PubMed PMID: 22444253
4 days) anterior myocardial infarction
and onset of energy-consuming autophagy which decreases the cellular ATP level
Derbyshire ER
Chemical Name: 2-[4-[2-Fluoro-5-[3-(6-methylpyridine-2-yl)-1H-pyrazol-4-yl] phenyl] pyrazol-1-yl]ethanol
AKBA Catalog No.:M8389-2 PubMed PMID: 22444253AKBA is an antiangiogenic and neuroprotective agent, reducing the impact of proliferative retinopathies, protecting neurons against ischemic injury involving the Nrf2 HO 1 pathway. AKBA is a naturally occurring pentacyclic triterpene isolated from the gum resin exudate from the stem of the tree B. serrata (frankincense). It selectively inhibits 5 lipoxygenase (IC50 = 1. 5 M) in an enzyme directed, nonredox, and noncompetitive manner. 2 3 acetyl 11
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