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is known to be an Akt inhibitor and to have an anti-tumor effect on several cancers
InChiKey: GBJVAVGBSGRRKN-JYEBCORGSA-N
InChi: InChI=1S/C17H13N3O/c1-20-10-11(12-5-2-3-7-15(12)20)9-13-16-14(19-17(13)21)6-4-8-18-16/h2-10H
21)22)8-12(7-10)18(23
3-b]pyridazin-3-yl]sulfanyl}quinoline
AC710 mesylate eridol D4 is known to be anAC710 is a potent, orally active, and selective platelet derived growth factor receptor family kinase inhibitor with potential anticancer activity. Its IC50 values are 1. 2, 2, 7. 7 and 10. 5 nM for KIT, FLT3, PDGFR and CSF1R respectively; Kd = 1. 3 nM for PDGFR.. AC710 causes tumor regression of leukemia cell xenografts in mice. AC710 also reduces joint swelling and inflammation in a mouse model of collagen induced arthritis. AC710 is now a