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AZD5582 results in cIAP1 degradation and caspase-3 cleavage within tumor cells and causes substantial tumor regressions following two weekly doses of 3
selective and competitive noncovalent inhibitor of SARS PLPro
PubMed PMID: 26268695
InChiKey: IVTVGDXNLFLDRM-HNNXBMFYSA-N
noradrenaline [norepinephrine]) suggesting that H3 antagonists have the potential to improve attention and impulsivity
KPT-276 Catalog No.:M10971-10 AZD5582 results in cIAP1 degradationKPT 276 is an orally bioavailable inhibitor of Exportin 1 (XPO1 CRM1) with anticancer activity. Product information CAS Number: 1421919 75 6 Molecular Weight: 426. 26 Formula: C16H10F8N4O Chemical Name: (2Z) 3 {3 [3,5 bis(trifluoromethyl)phenyl] 1H 1,2,4 triazol 1 yl} 1 (3,3 difluoroazetidin 1 yl)prop 2 en 1 one Smiles: O=C( C=C\N1C=NC(=N1)C1C=C(C=C(C=1)C(F)(F)F)C(F)(F)F)N1CC(F)(F)C1 InChiKey: JCHAWRDHMUSLMM UPHRSURJSA N InChi: InChI=1S C16H10F8N4O
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