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VX-745 provides IC50 of 56 and 52 nM for IL-1β and TNFα
32)44-25(4)38)20-26(22-37)21-34(41)28(35)19-23(2)31(34)40/h19-20
DMSO: 4oC for 3 month
Stransky N
Halofuginone HBr
11-Beta-hydroxyandrostenedione orphenamide VX-745 provides IC50 of 5611 Beta hydroxyandrostenedione (4 Androsten 11 ol 3,17 dione) is a steroid mainly found in the the adrenal origin (11 hydroxylase is present in adrenal tissue, but absent in ovarian tissue). 11 Beta hydroxyandrostenedione is a 11 hydroxysteroid dehydrogenase (11HSD) isozymes inhibitor. As 4 androstenedione increases, measuring plasma 11 Beta hydroxyandrostenedione can distinguish the adrenal or ovarian origin of hyperandrogenism. Product information
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