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1'-biphenyl]-3-yl]methoxy}phenyl)hex-4-ynoic acid
Formula: C21H18NO4
26(11):2284-2299
Hoestgaard-Jensen K
[O-][N+](=O)C1=CC2NC(=O)C(=O)NC=2C=C1N1C=NC=C1
PF-06650833 18998 1'-biphenyl]-3-yl]methoxy}phenyl)hex-4-ynoic acidPF 06650833 is a potent, selective and orally active inhibitor of interleukin 1 receptor associated kinase 4 (IRAK4) with IC50s of 0. 2 and 2. 4 nM in the cell and PBMC assay, respectively. PF 06650833 is used to treat diseases such as rheumatoid arthritis, lupus, and lymphomas. Product information CAS Number: 1817626 54 2 Molecular Weight: 361. 37 Formula: C18H20FN3O4 Chemical Name: 1 {[(2S,3S,4S) 3 ethyl 4 fluoro 5 oxopyrrolidin 2 yl]methoxy} 7
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