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involving the increment of BAX/Bcl-2 ratio
InChi: InChI=1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14
a structural analog of Linoleic acid with no a-carboxyl group
It also significantly inhibits JAK2 V617F
Cell Oncol (Dordr)
TVB-3166 tyl Dapsone D4 involving the increment of BAX/Bcl-2TVB 3166 is an orally available, reversible, and selective fatty acid synthase (FASN) inhibitor with IC50s of 42 nM and 81 nM for biochemical FASN and cellular palmitate synthesis, respectively. TVB 3166 induces apoptosis, and inhibits in vivo xenograft tumor growth. Product information CAS Number: 1533438 83 3 Molecular Weight: 384. 47 Formula: C24H24N4O Related CAS Number: 2097262 60 5 Chemical Name: 4 {1 [5 (4,5 dimethyl 1H pyrazol 3 yl) 2,4