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20(8):1167-74
Gopinathan S
A New Phenylpyrazoleanilide
InChi: InChI=1S/C20H20N4O3/c1-2-27-19(25)16-6-8-17(9-7-16)23-20(26)21-14-15-4-10-18(11-5-15)24-13-3-12-22-24/h3-13H
a New Fibroblast Growth Factor Receptor Tyrosine Kinase Inhibitor
TAS-301 - CAS# 193620-69-8 002euronal-LSB3i 20(8):1167-74TAS 301, CAS No. 193620 69 8, is a potent and selective constrictive remodeling regulator on renarrowing after balloon overstretch injury of porcine coronary artery. TAS 103 inhibits smooth muscle cell migration and proliferation. TAS 103 inhibits intimal thickening after balloon injury to rat carotid arteries. TAS 301 blocks receptor operated calcium influx and inhibits rat vascular smooth muscle cell proliferation induced by basic fibroblast growth
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