Wedelolactone 2098 Chemical Name: 2-amino-5-(3-(piperazin-1-yl)phenyl)-N-(pyridin-4-yl)nicotinamide

Chemical Name: 2-amino-5-(3-(piperazin-1-yl)phenyl)-N-(pyridin-4-yl)nicotinamide

CCC1=CC=C(CC2=CC=C3CO[C@]4(O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C3=C2)C=C1

Str•mberg K

L-685458 inhibits EpCAM production except in necrotic areas

BIO-acetoxime has anticonvulsant and anti-infection activity

Wedelolactone 2098 Chemical Name: 2-amino-5-(3-(piperazin-1-yl)phenyl)-N-(pyridin-4-yl)nicotinamideWedelolactone, a natural product from Ecliptae herba, suppresses LPS induced caspase 11 expression by directly inhibiting the IKK Complex[1]. Wedelolactone inhibits 5 lipoxygenase (5 Lox) (IC50~2. 5 M) activity by an oxygen radical scavenging mechanism. Wedelolactone induces caspase dependent apoptosis in prostate cancer cells via downregulation of PKC without inhibiting Akt[2]. Anti cancer, anti inflammatory, and antioxidant activities. Product