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InChiKey: GUVJPXABQYFWPD-GSZDNMEJSA-N
36(1):102-7
Liriodenine is against P-388
Significant deficits are observed after treatment with 2
which is associated with mitochondria-dependent signal pathway and involves p53 upregulation and caspase-3 activation pathway
PT 1 Catalog No.:M23080-C InChiKey: GUVJPXABQYFWPD-GSZDNMEJSA-NPT 1 is a selective activator of AMPK with EC50 value of 0. 3 M for AMPK 111 . AMP activated protein kinase (AMPK) is serine threonine protein kinase that involved in cellular energy homeostasis and acts as an energy sensor. AMPK is a heterotrimer and increases ATP generation . PT 1 is a selective AMPK activator. PT1 activated human AMPK 1394, AMPK 2398 and AMPK(111) with EC50 values of 8, 12 and 0. 3 M, respectively. PT1 exhibited maximum activity
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