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Small-molecule inhibitor of USP7/HAUSP ubiquitin protease stabilizes and activates p53 in cells
CAS Number: 1197996-80-7
Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened
1186/s12891-016-0995-x
Kikalishvili N
STAT3-IN-1 Catalog No.:M7387-2 Small-molecule inhibitor of USP7/HAUSP ubiquitinSTAT3 IN 1 (compound 7d) is an excellent, selective and orally active inhibitor of STAT3 with IC50 of 1. 82 M and 2. 14 M in HT29 and MDA MB 231 cells, respectively. STAT3 IN 1 induces apoptosis of tumor cells. Product information CAS Number: 2059952 75 7 Molecular Weight: 475. 53 Formula: C28H29NO6 Chemical Name: (E) N (4 ((E) 3,5 dimethoxystyryl)phenyl) 3 (3,4,5 trimethoxyphenyl)acrylamide Smiles: COC1=CC(=CC(=C1)OC) C=C C1C=CC(=CC=1)NC(=O) C=C