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PAF-AN-1 is a platelet activating factor receptor (PAF) antagonist
UK-370106 is found to be inactive (IC50 > 100 µM) vs zinc metalloproteases PCP and TACE and possesses the following inhibitory potencies vs MMP-2 (IC50 of 34
InChi: InChI=1S/C8H10ClN3O/c9-6-1-2-7(12-5-6)8(13)11-4-3-10/h1-2
and neuromuscular paralysis
and RARγ and may modify gene expression
Lp-PLA2-IN-1 ovalerylshikonin PAF-AN-1 is a platelet activatingLp PLA2 IN 1 is a potent Lipoprotein associated phospholipase A2 (Lp PLA2) inhibitor. Lp PLA2 IN 1 has the potential for atherosclerosis, Alzheimer's disease research. Product information CAS Number: 1420367 28 7 Molecular Weight: 468. 38 Formula: C21H17F5N4O3 Chemical Name: 8 [(3,5 difluoro 4 {[6 (trifluoromethyl)pyridin 3 yl]oxy}phenyl)methoxy] 1 methyl 1H,2H,3H,4H,6H [1,3]diazino[1,6 a]pyrimidin 6 one Smiles:
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