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SKP2-C25 exhibits potent antitumor activities in multiple animal models and cooperates with chemotherapeutic agents to reduce cancer cell survival
24 μM for DYRK1B and DYRK1A respectively
JIB-04 alters transcriptional programs in cancer but not in normal cells
SHP2 is a nonreceptor protein tyrosine phosphatase (PTP) encoded by the PTPN11 gene involved in cell growth and differentiation via the MAPK signaling pathway
Molecular Weight: 569
Py-ds-But-OSu - CAS# 115088-06-7 Library of Histone Demethylase SKP2-C25 exhibits potent antitumor activitiesDemethylzeylasteral (T 96), CAS No. 115088 06 7, the active component isolated from Tripterygium wilfordii Hook F., inhibits UDP glucuronosyltransferase (UGT) isoforms UGT1A6 and UGT2B7 with immunosuppressive effects. Product information CAS Number: 115088 06 7 Molecular Weight: 326. 39 Formula: C13H14N2O4S2 Synonym: SPDB Chemical Name: (2, 5 dioxopyrrolidin 1 yl) 4 (pyridin 2 yldisulfanyl)butanoate Smiles: O=C(CCCSSC1=CC=CC=N1)ON1C(=O)CCC1=O
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