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(S, R, S)-AHPC-Me dihydrochloride 0275 108(9):3689-94

SKU: 86804403053

4.5
USD80.00 USD108.00

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Description

108(9):3689-94

3)19-11-9-18(10-12-19)23(31)28-24(32)27-21-15-13-20(14-16-21)26-22(30)8-6-7-17-29(4)5

CAS Number: 482-89-3

INT-777 mitigates inflammatory response in human endometriotic stromal cells: A therapeutic implication for endometriosis

Smiles: [2H]C1=C(C#N)C([2H])=C([2H])C(NC2=NC(OC3C(C)=CC(=CC=3C)C#N)=C(Br)C(N)=N2)=C1[2H]

(S, R, S)-AHPC-Me dihydrochloride 0275 108(9):3689-94(S,R,S) AHPC Me dihydrochloride (VHL ligand 2 dihydrochloride) is the (S,R,S) AHPC based VHL ligand used in the recruitment of the von Hippel Lindau (VHL) protein. (S,R,S) AHPC Me dihydrochloride can be used to synthesize ARV 771, a von Hippel Landau (VHL) E3 ligase based BET PROTAC degrader. ARV 771 potently degrades BET protein in castration resistant prostate cancer (CRPC) cells with a DC50 <1 nM. Product information Molecular Weight: 517. 51

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