6% oral bioavailability in rats
MI-503 occupies the F9 and P13 pockets on menin
1021/ml200199c
Deoxyguanosine
IDH-C227 was used at 1-5 µM final concentration in vitro
Baccatin III 19346 6% oral bioavailability in ratsBaccatin III is a natural product isolated from Pacific yew tree and related species. Baccatin III reduces tumor progression by inhibiting the accumulation and suppressive function of MDSCs. Product information CAS Number: 27548 93 2 Molecular Weight: 586. 63 Formula: C31H38O11 Chemical Name: (1S,2S,3R,4S,7R,9S,10S,12R,15S) 4,12 bis(acetyloxy) 1,9,15 trihydroxy 10,14,17,17 tetramethyl 11 oxo 6 oxatetracyclo[11. 3. 1. 0,. 0,]heptadec 13 en 2 yl