SKI-178 Size:10mg solid H2O4S/c1-20-16(19)15(12-4-2-3-5-13(12)17)18-8-6-14-11(10-18)7-9-21-14

H2O4S/c1-20-16(19)15(12-4-2-3-5-13(12)17)18-8-6-14-11(10-18)7-9-21-14

30)31)12-23(13-22)38-15-18(2)34-16-38/h3-16H

tumor cell migration

It is the first line treatment given its moderate side effects compared to nifurtimox

CAS Number: 1014405-03-8

SKI-178 Size:10mg solid H2O4S/c1-20-16(19)15(12-4-2-3-5-13(12)17)18-8-6-14-11(10-18)7-9-21-14SKI 178 is a potent sphingosine kinase 1 (SphK1) and SphK2 inhibitor. SKI 178 is cytotoxic at IC50 concentrations ranging from 1. 8 to 0. 1 M in both drug sensitive and multi drug resistant cancer cell lines (i. e., MTR3, NCI ADR and HL60 VCR cells). SKI 178 induces apoptosis in a CDK1 dependent manner in human acute myeloid leukemia cell lines. Product information CAS Number: 1259484 97 3 Molecular Weight: 394. 42 Formula: C21H22N4O4 Chemical Name: