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The small molecule inhibitor
Cyclo(L-arginylglycyl-L-aspartyl-D-phenylalanyl-N-methyl-L-valyl)
but not obviously reduced
Smiles: CCC1=NN(CCO)C(CC)=C1OC1C=C(C=C(C=1)C#N)C#N
65% and 55%
TAK-875 er-5 The small molecule inhibitorTAK 875, is a potent, selective, and orally bioavailable GPR40 agonist, with a pharmacokinetic profile enabling long acting drug efficacy. TAK 875 showed potent plasma glucose lowering action and insulinotropic action during an oral glucose tolerance test in female Wistar fatty rats with impaired glucose tolerance. TAK 875 is currently in clinical trials for the treatment of type 2 diabetes mellitus. Product information CAS Number: 1000413 72 8
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