Metolazone uolin-1 displays a higher solubility

displays a higher solubility

Binding Modes of Small-Molecule Inhibitors to the EED Pocket of PRC2

It induces degradation of EGFR in OVCAR8 cells

Chemical Name: 4-[3-(difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide

CAS Number: 307510-92-5

Metolazone uolin-1 displays a higher solubilityMetolazone is a thiazide like diuretic. It is primarily used to treat congestive heart failure and high blood pressure. Metolazone indirectly decreases the amount of water reabsorbed into the bloodstream by the kidney, so that blood volume decreases and urine volume increases. This lowers blood pressure and prevents excess fluid accumulation in heart failure. Metolazone is sometimes used together with loop diuretics such as furosemide or bumetanide,