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also known as Mutant IDH1 inhibitor
Smiles: CC(=O)[C@]1(N)CC2=C([C@H](C1)O[C@H]1C[C@H](O)[C@H](O)CO1)C(O)=C1C(C(=O)C3=CC=CC=C3C1=O)=C2O
serum hydroxyproline (HOP) levels
Smiles: CN1CCN(CC1)C1C=CC(=CC=1)NC1=NC2=C(C=N1)C=C(C(=O)N2CC)C1=CC=C(C=C1Cl)C1=CN=CS1
Macitentan is a dual ERA
Betulinic acid - CAS# 472-15-1 Catalog No.:M10557-10 also known as Mutant IDH1Betulinic acid is a pentacyclic lupane type triterpene derivative of betulin (isolated from the bark of Betula alba, the common white birch) with antiinflammatory, anti HIV and antineoplastic activities. Betulinic acid induces apoptosis through induction of changes in mitochondrial membrane potential, production of reactive oxygen species, and opening of mitochondrial permeability transition pores, resulting in the release of mitochondrial apogenic
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