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Formula: C25H26FN5O2
which transport various molecules across extra- and intra-cellular membranes
a selective endothelin ET(B) receptor antagonist
Pfaffendorf M
CAS Number: 38183-12-9
CU-3 aflumizone Formula: C25H26FN5O2CU 3 is the racemate of (5Z,2E) CU 3. (5Z,2E) CU 3 is a potent and selective inhibitor against the isozyme of DGK with an IC50 value of 0. 6 M, competitively inhibits the affinity of DGK for ATP with a Km value of 0. 48 mM. (5Z,2E) CU 3 targets the catalytic region, but not the regulatory region of DGK. (5Z,2E) CU 3 has antitumoral and proimmunogenic effects, enhances the apoptosis of cancer cells and the activation of T cells. Product information CAS
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