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68047-06-3
PubMed PMID: 22948716
At the end of the study
CAS Number: 2451573-87-6
Chemical Name: N-methyl-4-(4-(3-(trifluoromethyl)benzamido)phenoxy)picolinamide
PKI-587 stin 68047-06-3PKI 587is an agent targeting the phosphatidylinositol 3 kinase (PI3K) and mammalian target of rapamycin (mTOR) in the PI3K mTOR signaling pathway, with potential antineoplastic activity. Upon intravenous administration, PI3K mTOR kinase inhibitor PKI 587 inhibits both PI3K and mTOR kinases, which may result in apoptosis and growth inhibition of cancer cells overexpressing PI3K mTOR. Activation of the PI3K mTOR pathway promotes cell growth, survival,
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