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The intraperitoneal administration of Alniditan ED50=9 μg/kg dose dependly reduces [125I]-BSA extravasation in the rat meninges when done 30 min before stimulation
Na/c1-3-16(4-2)14(20)10(8-15)5-9-6-11(17(21)22)13(19)12(18)7-9
Biorobin (Kaempferol 3-O-robinobioside) inhibits the in vitro proliferative response of human T-cells (IC50=25 mg/mL)
Smiles: CC1(C)C2CC(O)C3=C(C(=O)CC4(C)C(CC(O)C43C)C(C)CCC(O)=O)C2(C)CCC1=O
528(1):67-72
Phrixotoxin 3 TFA Catalog No.:M17683-C The intraperitoneal administration of AlniditanPhrixotoxin 3 TFA is a potent blocker of voltage gated sodium channels, with IC50s of 0. 6, 42, 72, 288, 610 nM for NaV1. 2, NaV1. 3, NaV1. 4, NaV1. 1 and NaV1. 5, respectively. Phrixotoxin 3 TFA modulates voltage gated sodium channels with properties similar to those of typical gating modifier toxins, both by causing a depolarizing shift in gating kinetics and by blocking the inward component of the sodium current. Product information Molecular
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