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Radotinib Catalog No.:M10972-2 PubMed Central PMCID: PMC4101245

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Description

PubMed Central PMCID: PMC4101245

is expressed during embryonal development and is absent in most normal

PubMed PMID: 31199090

Clarithromycin prevents bacteria by acting as a protein synthesis inhibitor

GO-6976 blocked neurotrophin-induced signaling and autophosphorylation of neurotrophin-specific tyrosine kinase (Trk) receptors

Radotinib Catalog No.:M10972-2 PubMed Central PMCID: PMC4101245Radotinib, also known as IY 5511, is an orally available, a second generation tyrosine kinase inhibitor of Bcr Abl fusion protein and the platelet derived growth factor receptor (PDGFR), with potential antineoplastic activity. Upon administration, radotinib specifically inhibits the Bcr Abl fusion protein, an abnormal enzyme expressed in Philadelphia chromosome positive chronic myeloid leukemia (CML) cells. In addition, this agent also inhibits PDGFR

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