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Target: I1-RMoxonidine is a centrally acting antihypertensive agent
Smiles: C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C
InChi: InChI=1S/C34H28N4O4/c1-34-31(39)24(36(2)33(41)18-10-4-3-5-11-18)16-25(42-34)37-22-14-8-6-12-19(22)27-28-21(17-35-32(28)40)26-20-13-7-9-15-23(20)38(34)30(26)29(27)37/h3-15
9 nM (BT-474 (breast))
Chemical Name: 1-(2-amino-6-(3
ARN-3236 10959 Target: I1-RMoxonidine is a centrallyARN 3236 is an oral active and selective inhibitor of salt inducible kinase 2 (SIK2), with IC50s of <1 nM, 21. 63 nM and 6. 63 nM for SIK2, SIK1 and SIK3, respectively. Has anti cancer activity. Product information CAS Number: 1613710 01 2 Molecular Weight: 336. 41 Formula: C19H16N2O2S Chemical Name: 3 (2,4 dimethoxyphenyl) 4 (thiophen 3 yl) 1H pyrrolo[2,3 b]pyridine Smiles: COC1=CC(=CC=C1C1=CNC2=NC=CC(=C12)C1=CSC=C1)OC InChiKey: WEHOIIGXTMKVRG