OICR-0547 Catalog No.:M26124-C 4 hours and a CCmax

4 hours and a CCmax of 1

39 and Asp972

RSV604 (A-60444) racemate is a racemic mixture

PF-06409577 is orally bioavailable AMPK activator with EC50 of 7 nM for α1β1γ1 in the TR-FRET assay and it shows no detectable inhibition of hERG in a patch-clamp assay (100 μM) and was not an inhibitor (IC50 > 100 μM) of the microsomal activities of major human cytochrome P450 isoforms

Smiles: CC1C=CC(=CC=1)C1=C(C=NN1C)C1=NN(C)C2=NC=NC(=C12)N1C[C@H](CC1)N1CCCCC1

OICR-0547 Catalog No.:M26124-C 4 hours and a CCmaxOICR 0547 is a closely related derivative of OICR 9429. OICR 9429 is a novel small molecule antagonist of the Wdr5 MLL interaction, while OICR 0547 is an inactive control compound that no longer binds to WDR5. Product information CAS Number: 1801873 49 3 Molecular Weight: 542. 55 Formula: C28H29F3N4O4 Chemical Name: N [4 (morpholin 4 yl) 3' [(morpholin 4 yl)methyl] [1,1' biphenyl] 3 yl] 6 oxo 4 (trifluoromethyl) 1,6 dihydropyridine 3 carboxamide