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Solubility: DMSO: ≥ 51 mg/mL
ZXH-3-26 is a selective PROTAC BRD4 degrader
92%) and increases the proportion of cells in G0-G1 phase and to a lesser extent in G2/M
The proliferation and transformation of the HCT15
7-trihydroxy-9a
Guggulsterone - CAS# 95975-55-6 Catalog No.:M12290-10 Solubility: DMSO: ≥ 51 mg/mLGuggulsterone is a plant sterol derived from the gum resin of the tree Commiphora wightii. Guggulsterone inhibits the growth of a wide variety of tumor cells and induces apoptosis through down regulation of antiapoptotic gene products (IAP1, xIAP, Bfl 1 A1, Bcl 2, cFLIP and survivin), modulation of cell cycle proteins (cyclin D1 and c Myc), activation of caspases and JNK, inhibition of Akt. Guggulsterone, a farnesoid X receptor (FXR) antagonist,