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Epub 2012 Oct 25
PubMed PMID: 28138036
MTEP HCl is a potent and selective non-competitive mGlu5 antagonist/negative allosteric modulator
MCT-14-1077
CAS Number: 520-18-3
FM-479 11378 Epub 2012 Oct 25FM 479 is the negative control of FM 381 (HY 102046) and has no activity on JAK3 or other kinases. FM 381 is a potent covalent reversible inhibitor of JAK3 targeting the unique Cys909. FM 381 has an IC50 of 127 pM for JAK3, with 410, 2700 and 3600 fold selectivity over JAK1, JAK2 and TYK2, respectively. Product information CAS Number: 2226521 64 6 Molecular Weight: 442. 51 Formula: C25H26N6O2 Chemical Name: (2E) 2 cyano 3 (5 {3 cyclohexyl 10 methyl 3,
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