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GCN2-IN-6 L246) Study of Na

SKU: 69731408850

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Description

Study of Na

Chrysophanic acid (Chrysophanol) treatment in SNU-C5 cells inhibits EGF-induced phosphorylation of EGFR and suppresses activation of downstream signaling molecules

Epoxomicin is an irreversible

Chemical Name: 2-{4-[(5

InChiKey: FBOUYBDGKBSUES-VXKWHMMOSA-N

GCN2-IN-6 L246) Study of NaGCN2 IN 6 (Compound 6d) is a potent, and orally available GCN2 inhibitor confirmed by in house enzymatic (IC50 of 1. 8 nM) and cellular assays (IC50 of 9. 3 nM). GCN2 IN 6 is also a eIF2 kinase PERK inhibitor with an IC50 of 0. 26 nM (in enzymatic assay) and 230 nM (in cells). Product information CAS Number: 2183470 09 7 Molecular Weight: 485. 29 Formula: C19H12Cl2F2N4O3S Chemical Name: N {3 [2 (2 aminopyrimidin 5 yl)ethynyl] 2,4 difluorophenyl} 2,5

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