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Diosgenin is the precursor for the semisynthesis of progesterone which in turn was used in early combined oral contraceptive pills
and affects DNA repair pathways beyond homologous recombination (HR)
Rosiglitazone Maleate is a potent and selective activator of peroxisome proliferator-activated receptor gamma (PPAR gamma)
PubMed PMID: 25583820
This strategy preferentially targets primary Bcr/Abl(+) hematopoietic cells and exhibits enhanced in vivo activity
Tenofovir alafenamide hemifumarate tegravir (MK-0518) Diosgenin is the precursor forTenofovir alafenamide (TAF, GS 7340) hemifumarate is a prodrug of tenofovir but results in significantly higher intracellular tenofovir concentrations and lower serum levels. Tenofovir alafenamide is a novel nucleotide reverse transcriptase inhibitor for the treatment of HIV 1 infection. Product information CAS Number: 1392275 56 7 Molecular Weight: 1069. 00 Formula: C46H62N12O14P2 Synonym: Tenofovir alafenamide fumarate (2: 1) Chemical Name: