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VU-0357121 shows weaker cooperativity in the Ca2+ mobilization assay in the low-expressing HEK293A-mGlu5 cell line
2018 Jul 21
InChi: InChI=1S/C9H5ClN4/c10-7-2-1-3-8(4-7)13-14-9(5-11)6-12/h1-4
InChiKey: FODTZLFLDFKIQH-YGPNKWNYSA-N
NL-1 inhibits SUPB15
BI-1347 ozopran VU-0357121 shows weaker cooperativity inBI 1347 is a potent CDK8 inhibitor extracted from patent WO2017202719A1, product I 003, has an IC50 of 1. 1 nM. Product information CAS Number: 2163056 91 3 Molecular Weight: 356. 42 Formula: C22H20N4O Chemical Name: 2 {4 [4 (isoquinolin 4 yl)phenyl] 1H pyrazol 1 yl} N,N dimethylacetamide Smiles: CN(C)C(=O)CN1C=C(C=N1)C1C=CC(=CC=1)C1=CN=CC2C=CC=CC=21 InChiKey: WULUGQONDYDNKY UHFFFAOYSA N InChi: InChI=1S C22H20N4O c1 25(2)22(27)15 26 14 19(12 24 26)16
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