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OSU-03012 does not suppress PDK1 or AKT activity or induce cellular apoptosis but induces autophagy in Huh7 cells
1-dimethylethyl)phenoxy]ethyl]-N-methylglycine hydrochloride
and vascular regrowth contribute to the antitumor properties of dual mTORC1/mTORC2 inhibitors
Baladandayuthapani V
FTD is the active antitumor component of TAS-102 (Trifluridine-tipiracil hydrochloride mixture)
Nitidine chloride xylamine D5 succinate OSU-03012 does not suppress PDK1Nitidine chloride, a potential anti malarial lead compound derived from Zanthoxylum nitidum (Roxb) DC, exerts potent anticancer activity through diverse pathways, including inducing apoptosis, inhibiting STAT3 signaling cascade, DNA topoisomerase 1 and 2A, ERK and c Src FAK associated signaling pathway. Nitidine chloride inhibits LPS induced inflammatory cytokines production via MAPK and NF kB pathway. Product information CAS Number: 13063 04 2
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