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InChi: InChI=1S/C24H29N3O2/c28-23(12-11-21-8-6-15-25-19-21)26-16-5-4-7-20-13-17-27(18-14-20)24(29)22-9-2-1-3-10-22/h1-3
Formula: C35H49F2N7O4
the active NEPi LBQ657 had no discernible effects
07 µM and ~0
18(23)24)15(12)17(22)16(13)21/h10-11
STO-609 - CAS# 52029-86-4 0012 InChi: InChI=1S/C24H29N3O2/c28-23(12-11-21-8-6-15-25-19-21)26-16-5-4-7-20-13-17-27(18-14-20)24(29)22-9-2-1-3-10-22/h1-3STO 609, CAS No. 52029 86 4, is a specific inhibitor of the Ca(2+) calmodulin dependent protein kinase kinase. STO 609 inhibits the activities of recombinant CaM KK alpha and CaM KK beta isoforms, with K(i) values of 80 and 15 ng ml, respectively, and also inhibits their autophosphorylation activities. STO 609 is highly selective for CaM KK without any significant effect on the downstream CaM kinases (CaM KI and IV), and the IC(50) value of the
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