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Formula: C7H6ClN3O4S2
2016 Jul 26
Formula: C43H63NO11
as well as its association with HIF-1α
The Ki values for inhibition of Cl-current in wild-type
RJR-2403 (oxalate) 716556 Formula: C7H6ClN3O4S2Metanicotine, also known as RJR 2403 and TC 2403, is a neuronal nicotinic receptor agonist, showing high selectivity for the 42 subtype. Metanicotine has high affinity to rat brain cortex (Ki = 26 + 3 nM). Metanicotine is comparable to nicotine in activating rat thalamic synaptosomes (EC50 = 732 + 155 nM and Emax = 91 + 8% for RJR 2403; EC50 = 591 + 120 nM and Emax = 100 + 25% for nicotine) . Chronic administration of RJR 2403 in combination with low