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RS-25344 hydrochloride - CAS# 152815-28-6 Size:Contact [email protected] for quotation PROTAC CRABP-II Degrader-3 is a

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Description

PROTAC CRABP-II Degrader-3 is a potent cellular retinoic acid binding protein (CRABP-II) degrader based on cIAp1

8-difluoro-4-oxo-1

5-6 hours) increases PERK dimerization by phosphorylation and IRE1-α oligomerization within 30 minutes in KMS-12-PE confirming accumulation of misfolded ER proteins

twice weekly for 3 weeks) decreases the tumor volume and increases survival in mice with subcutaneous sonic hedgehog (SHH)-subtype medulloblastoma

6-24 hours) is able to induce caspase-2 activation

RS-25344 hydrochloride - CAS# 152815-28-6 Size:Contact [email protected] for quotation PROTAC CRABP-II Degrader-3 is aRS 25344 hydrochloride is a selective cAMP phosphodiesterase 4 (PDE 4; PDE IV) inhibitor with an IC50 of 0. 28 nM in human lymphocytes. RS 25344 hydrochloride has only weak inhibitory effects on PDE I, II, III (IC50 of >100 M, 160 M, 330 M, respectively). RS 25344 hydrochloride has anti inflammatory, memory and cognition enhancing, and antineoplastic effects. Product information CAS Number: 152815 28 6 Molecular Weight: 411. 80 Formula: C19H14ClN5O4

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