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12)62)31-42(55)34(3)27-37(6)48(57)49(65-10)47(56)36(5)26-32/h13-15
PIM kinases play key roles in cell cycle progression and apoptosis inhibition and may be overexpressed in various malignancies
Solubility: DMSO : ≥ 35 mg/mL (82
67 mg/mL (187
is a potent and selective inhibitor of IDH2 R140Q and R172K mutant first reported in patent WO 2013102431
Bosutinib D8 14306 12)62)31-42(55)34(3)27-37(6)48(57)49(65-10)47(56)36(5)26-32/h13-15Bosutinib D8 (SKI 606 D8) is a deuterium labeled Bosutinib. Bosutinib is a dual Src Abl inhibitor with IC50s of 1. 2 nM and 1 nM, respectively. Product information Molecular Weight: 538. 50 Formula: C26H29Cl2N5O3 Chemical Name: 4 ((2, 4 dichloro 5 methoxyphenyl)amino) 6 methoxy 7 (3 (4 methylpiperazin 1 yl 2, 2, 3, 3, 5, 5, 6, 6 d8)propoxy)quinoline 3 carbonitrile Smiles:
US$ 1413.00
US$ 1027.50