Temocapril Hydrochloride Catalog No.:M9100-10 InChiKey: VIYFPAMJCJLZKD-UHFFFAOYSA-L

InChiKey: VIYFPAMJCJLZKD-UHFFFAOYSA-L

mouse-adapted H1N1 influenza PR8 virus with 60% survival

release an amount of LDH (12

5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy}-4-formyl-4-hydroxy-5-methyloxolan-2-yl]oxy}-2

PubMed PMID: 12855627

Temocapril Hydrochloride Catalog No.:M9100-10 InChiKey: VIYFPAMJCJLZKD-UHFFFAOYSA-LTemocapril is a prodrug of the ACE inhibitor, temocaprilat (IC50 = 3. 6 and 7. 6 nM in isolated rat lung and aorta, respectively). 1 Upon oral administration it is rapidly deesterified to the active form, which remains long acting until excreted in bile and urine. 1 In clinical trials, it has been used to reduce blood pressure, improve endothelial dysfunction, and prevent vascular remodeling, as well as improve insulin sensitivity and renal function