TRV 130 Catalog No.:M8976-10 JW74 shows a reduction of

JW74 shows a reduction of canonical Wnt signaling in the ST-Luc assay with an IC50 of 790 nM

Chemical Name: 2-Cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy) quinazolin-4-amine

thus leading to increased neuron excitability

27(10): 1432-1445

inflammatory infiltrate

TRV 130 Catalog No.:M8976-10 JW74 shows a reduction ofOliceridine is a mu opioid receptor ligand. Oliceridine is now discontinued since it was recently listed as a controlled substance. Product information CAS Number: 1401028 24 7 Molecular Weight: 386. 55 Formula: C22H30N2O2S Synonym: TRV 130 Chemical Name: [(3 methoxythiophen 2 yl)methyl]({2 [(9R) 9 (pyridin 2 yl) 6 oxaspiro[4. 5]decan 9 yl]ethyl})amine Smiles: COC1C=CSC=1CNCC[C@]1(CCOC2(C1)CCCC2)C1=CC=CC=N1 InChiKey: DMNOVGJWPASQDL OAQYLSRUSA N InChi: