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Methotrexate-d3 Catalog No.:M24852-C 6R)-2-[(2R

SKU: 61165293848

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Description

6R)-2-[(2R

6-160 mg/kg) increases urine volume and sodium and chloride excretion in a dose-dependent fashion

and 400 mg/kg

CAS Number: 685506-42-7

and evaluation of indolinonesas inhibitors of the transforming growth factor β receptor I (TGFβRI)

Methotrexate-d3 Catalog No.:M24852-C 6R)-2-[(2RMethotrexate d3 (Amethopterin d3) is the deuterium labeled Methotrexate. Methotrexate (Amethopterin), an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute

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