AT-406 nbolone acetate 23)28)14-3-6-20(27)29-13-14/h3

23)28)14-3-6-20(27)29-13-14/h3

CAS Number: 79660-72-3

COC1=CC2=C(NC3=CC(Br)=CC=C3)N=CN=C2C=C1OC

also known as DGAT-3

CN(CCCC(C#N)(C(C)C)C1=CC(OC)=C(C=C1)OC)CCC1C=C(OC)C(=CC=1)OC

AT-406 nbolone acetate 23)28)14-3-6-20(27)29-13-14/h3DeBio 1143, also known as AT 406, ARRY 334543and SM 406, is an orally bioavailable inhibitor of IAP (Inhibitor of Apoptosis Protein) family of proteins with potential apoptotic inducing and antineoplastic activity. AT 406 selectively inhibits the biological activity of IAP proteins, including X chromosome linked IAP (XIAP), the cellular IAPs 1 (c IAP1) and 2 (c IAP2) and melanoma inhibitor of apoptosis protein (ML IAP). This may restore and promote