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40(3):472-478
CN(C)CCN1C(=O)[C@H](OC(C)=O)[C@@H](SC2=CC=CC=C12)C1C=CC(=CC=1)OC
InChiKey: JCINBYQJBYJGDM-UHFFFAOYSA-N
NSC 609669
InChi: InChI=1S/C25H36N6O4S/c1-5-8-20-22-23(31(4)29-20)25(32)28-24(27-22)19-16-18(10-11-21(19)35-15-6-2)36(33
Letrozole - CAS# 112809-51-5 Size:Solid 10 mg 40(3):472-478Letrozole, also known as CGS 20267, is a nonsteroidal inhibitor of estrogen synthesis with antineoplastic activity. As a third generation aromatase inhibitor, letrozole selectively and reversibly inhibits aromatase, which may result in growth inhibition of estrogen dependent breast cancer cells. Aromatase, a cytochrome P 450 enzyme localized to the endoplasmic reticulum of the cell and found in many tissues including those of the premenopausal ovary,
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