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InChiKey: PLYSCVSCYOQVRP-UHFFFAOYSA-N
Chemical Name: ethyl 2-amino-8-(1
InChi: InChI=1S/C25H31N5O4/c1-16-13-30(14-17(2)34-16)25-27-23-20(24(28-25)29-8-10-33-11-9-29)5-6-21(26-23)18-4-7-22(32-3)19(12-18)15-31/h4-7
Chemical Name: GW806742X
but has no inhibitory activity against c-Met-Y1230C with IC50 of >10 μM
Volasertib Catalog No.:M10873-10 InChiKey: PLYSCVSCYOQVRP-UHFFFAOYSA-NVolasertib, also known as BI 6727, is a dihydropteridinone Polo like kinase 1 (Plk1) inhibitor with potential antineoplastic activity. BI 6727 selectively inhibits Plk1, inducing selective G2 M arrest followed by apoptosis in a variety of tumor cells while causing reversible cell arrest at the G1 and G2 stage without apoptosis in normal cells. BI 6727 is highly potent (enzyme IC(50) = 0. 87 nmol L, EC(50) = 11 37 nmol L on a panel of cancer cell
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